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簡要描述：Uric Acid 69-93-2An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE.
產(chǎn)品型號：abs47027201廠商性質(zhì)：生產(chǎn)廠家更新時間：2025-12-02訪 問 量：751產(chǎn)品分類
Product Category詳細介紹
| 品牌 | absin | CAS | 69-93-2 |
|---|---|---|---|
| 分子式 | C5H4N4O3 | 純度 | 99% |
| 分子量 | 168.11 | 貨號 | abs47027201 |
| 規(guī)格 | 100mg | 供貨周期 | 現(xiàn)貨 |
| 主要用途 | is the final oxidation | 應用領域 | 化工,生物產(chǎn)業(yè),農(nóng)林牧漁,制藥/生物制藥,綜合 |
Uric Acid 69-93-2
| 產(chǎn)品描述 | |
| 描述 | An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN. |
| 純度 | 99% |
| 儲存/保存方法 | Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution. |
| 基本信息 | |
| 別名 | 尿酸 |
| 外觀 | 白色結晶 |
| 可溶性/溶解性 | 10 mM in DMSO |
| 生物活性 | |
| In vitro(體外研究) | Uric acid activates NFκB in a variety of cell culture models including proximal tubular cells. Uric acid suppresses 1-α hydroxylase mRNA and protein expression in dose dependent and time dependent manner. |
| In vivo(體內(nèi)研究) | Uric acid is synthesized mainly in the liver, intestines and the vascular endothelium as the end product of an exogenous pool of purines, and endogenously from damaged, dying and dead cells, whereby nucleic acids, adenine and guanine, are degraded into uric acid. Uric acid is a strong reactive oxygen species (ROS) and peroxynitrite scavenger and antioxidant. Uric acid may exert fundamental roles in tissue healing via initiating the inflammatory process that is necessary for tissue repair, scavenging oxygen free radicals, and mobilizing progenitor endothelial cells. |
| 參考文獻 | |
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| 研究領域 | |
| 研究領域 | Immunology Drug DiscoverySmall Molecule DrugLead Compound Discovery |
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