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簡要描述：Brivudine 69304-47-8描述Brivudine is an antiviral drug used in the treatment of herpes zoster.
產(chǎn)品型號：abs47027261廠商性質(zhì)：生產(chǎn)廠家更新時間：2025-12-04訪 問 量：761產(chǎn)品分類
Product Category詳細(xì)介紹
| 品牌 | absin | CAS | 69304-47-8 |
|---|---|---|---|
| 分子式 | C11H13BrN2O5 | 純度 | 99% |
| 分子量 | 333.14 | 貨號 | abs47027261 |
| 規(guī)格 | 5mg | 供貨周期 | 現(xiàn)貨 |
| 主要用途 | used in the treatment of herpes zoster | 應(yīng)用領(lǐng)域 | 化工,生物產(chǎn)業(yè),農(nóng)林牧漁,制藥/生物制藥,綜合 |
Brivudine 69304-47-8
| 產(chǎn)品描述 | |
| 描述 | Brivudine is an antiviral drug used in the treatment of herpes zoster. |
| 純度 | 99% |
| 儲存/保存方法 | Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution. |
| 基本信息 | |
| 別名 | 溴fu定；溴比夫定； Bromovinyldeoxyuridine；BVDU |
| 外觀 | 白色至淡黃色結(jié)晶性粉末 |
| 可溶性/溶解性 | DMSO : ≥330 mg/mL |
| 生物活性 | |
| 靶點(diǎn) | CMV |
| In vitro(體外研究) | Brivudine is an analog of thymidine, and is incorporated into the viral DNA. It blocks the action of DNA polymerases, thus inhibiting viral replication. It has a stronger antiviral effect against the varicella-zoster virus compared with reference compounds such as aciclovir or penciclovir. It has high, selective activity against varicella zoster virus (VZV), inhibiting VZV replication, possibly through competitive inhibition of viral DNA polymerase, or by acting as an alternative substrate to deoxythymidine triphosphate, causing viral DNA strand breakage. |
| In vivo(體內(nèi)研究) | At a dose of 125 mg once daily, brivudine has proved to be superior to aciclovir with respect to reducing the period of new blister production, and has shortened the duration of post-herpetic neuralgia. |
| 參考文獻(xiàn) | |
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| 研究領(lǐng)域 | |
| 研究領(lǐng)域 | MetabolismTypes of disease Drug DiscoverySmall Molecule DrugLead Compound Discovery |
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