Ebselen 60940-34-3

簡要描述：Ebselen 60940-34-3
Ebselen is a organoselenium compound with anti-inflammatory, anti-oxidant and cytoprotective activity。

產(chǎn)品咨詢聯(lián)系我們

產(chǎn)品分類

Product Category

查看全部

詳細介紹

品牌	absin	CAS	60940-34-3
分子式	C13H9NOSe	純度	＞98%
分子量	274.18	貨號	abs47027330
規(guī)格	5mg	供貨周期	現(xiàn)貨
主要用途	is a organoselenium	應用領域	化工,生物產(chǎn)業(yè),農(nóng)林牧漁,制藥/生物制藥,綜合

Ebselen 60940-34-3

產(chǎn)品描述
描述	Ebselen is a organoselenium compound with anti-inflammatory, anti-oxidant and cytoprotective activity. Ebselen acts as a glutathione peroxidase mimetic and is thereby able to prevent cellular damage induced by reactive oxygen species (ROS). In addition, this agent inhibits the activity of a variety of enzymes including nitric oxide synthase (NOS), 5-lipoxygenase, cyclooxygenase, protein kinase C (PKC), NADPH oxidase and gastric H+/K+-ATPase. Furthermore, ebselen may be neuroprotective due to its ability to neutralize free radicals upon NMDA receptor activation thus, reducing lipoperoxidation mediated by glutamate-induced excitotoxicity.
純度	＞98%
儲存/保存方法	Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
基本信息
別名	依布硒；SPI-1005； PZ-51； CCG-39161
外觀	Yellow to beige Crystalline Powder
可溶性/溶解性	DMSO : 50 mg/mL (182.36 mM）
生物活性
靶點	COX
參考文獻
參考文獻	1. Schewe T. Gen Pharmacol, 2009, 26 (6): 1153–69. 2. Parnham M, et al. Expert Opin Investig Drugs, 2000, 9 (3): 607–19.

研究領域
研究領域	Immunology Neuroscience CancerTumor immunology MetabolismTypes of disease Drug DiscoverySmall Molecule DrugLead Compound Discovery

Ebselen 60940-34-3溫馨提示：本產(chǎn)品僅作科研實驗使用，不支持臨床等研究

產(chǎn)品咨詢