Azelaic acid 123-99-9

簡要描述：Azelaic acid 123-99-9
Azelaic acid is a saturated dicarboxylic acid found naturally in wheat, rye, and barley.

產(chǎn)品型號：abs47027394
廠商性質(zhì)：生產(chǎn)廠家
更新時間：2025-12-10
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品牌	absin	CAS	123-99-9
分子式	C9H16O4	純度	＞98%
分子量	188.22	貨號	abs47027394
規(guī)格	50mg	供貨周期	現(xiàn)貨
主要用途	is a saturated dicarboxylic acid	應(yīng)用領(lǐng)域	化工,生物產(chǎn)業(yè),農(nóng)林牧漁,制藥/生物制藥,綜合

Azelaic acid 123-99-9

產(chǎn)品描述
描述	Azelaic acid is a saturated dicarboxylic acid found naturally in wheat, rye, and barley. It is a natural substance that is produced by Malassezia furfur (also known as Pityrosporum ovale), a yeast that lives on normal skin. It is effective against a number of skin conditions, such as mild to moderate acne, when applied topically in a cream formulation of 20%. It works in part by stopping the growth of skin bacteria that cause acne, and by keeping skin pores clear. Azelaic acid's antimicrobial action may be attributable to inhibition of microbial cellular protein synthesis.
純度	＞98%
儲存/保存方法	Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
基本信息
別名	壬二酸；Nonanedioic acid
外觀	白色粉末
可溶性/溶解性	DMSO : 35 mg/mL (186 mM) Ethanol : 35 mg/mL (186 mM) Water : 34 mg/mL (180.6 mM)
生物活性
In vitro(體外研究)	AZ(Azelaic acid) combined with taurine (Tau) show more inhibitory effects in melanocytes than the treatment of AZ alone. AZ combined with Tau inhibits the melanin production and tyrosinase activity of B16F10 melanoma cells without significant cytotoxicity. Also inhibitory effects after treatment with these combined chemical are stronger than AZ alone on melanogenesis.
In vivo(體內(nèi)研究)	Azelaic acid exhibits an anti-atherogenic effect. Its athero-protective effect is not related to changes in plasma lipid content. Azelaic acid supplementation decreases the level of CD68 macrophage marker by 34% (p.
參考文獻(xiàn)
參考文獻(xiàn)	1. Schallreuter KU, Wood JM. Cancer Lett. 1987 Sep;36(3):297-305. 2. Stamatiadis D, et al. Br J Dermatol. 1988 Nov;119(5):627-32. 3. Imming P, et al. Nat Rev Drug Discov. 2006 Oct; 5(10):821-34. 4. Picardo M, et al. Biochem Pharmacol. 1985 May 15;34(10):1653-8. 5. Hojo Y, et al. Circ Res. 2002 Oct 18; 91(8):712-8.

研究領(lǐng)域
研究領(lǐng)域	Immunology Drug DiscoverySmall Molecule DrugLead Compound Discovery

Azelaic acid 123-99-9溫馨提示：本產(chǎn)品僅作科研實(shí)驗使用，不支持臨床等研究

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Azelaic acid 123-99-9

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