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18438616290
簡(jiǎn)要描述：Desipramine hydrochloride 58-28-6Desipramine Hydrochloride a secondary amine tricyclic antidepressant (TCA), is the hydrochloride salt form of desipramine.
產(chǎn)品型號(hào)：abs47027434廠商性質(zhì)：生產(chǎn)廠家更新時(shí)間：2025-12-11訪 問(wèn) 量：786產(chǎn)品分類(lèi)
Product Category詳細(xì)介紹
| 品牌 | absin | CAS | 58-28-6 |
|---|---|---|---|
| 分子式 | C18H23ClN2 | 純度 | ＞98% |
| 分子量 | 302.84 | 貨號(hào) | abs47027434 |
| 規(guī)格 | 100mg | 供貨周期 | 現(xiàn)貨 |
| 主要用途 | is the hydrochloride salt | 應(yīng)用領(lǐng)域 | 化工,生物產(chǎn)業(yè),農(nóng)林牧漁,制藥/生物制藥,綜合 |
Desipramine hydrochloride 58-28-6
| 產(chǎn)品描述 | |
| 描述 | Desipramine Hydrochloride a secondary amine tricyclic antidepressant (TCA), is the hydrochloride salt form of desipramine. In the central nervous system (CNS), desipramine hydrochloride blocks the re-uptake of neurotransmitters, including norepinephrine and serotonin. This leads to an increase in the amount of these neurotransmitters in the synaptic cleft and prolongs their activities postsynaptically. |
| 純度 | ＞98% |
| 儲(chǔ)存/保存方法 | Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution. |
| 基本信息 | |
| 別名 | 鹽酸去甲咪嗪 |
| 外觀 | white to off-white powder |
| 可溶性/溶解性 | DMSO : 83.3 mg/mL (275.06 mM; Need ultrasonic and warming) |
| 生物活性 | |
| 靶點(diǎn) | 5-HT Receptor |
| In vivo(體內(nèi)研究) | Treatment of rats with Desipramine hydrochloride for 14 days reduces norepinephrine transporter (NET) expression in a dose-dependent manner, as indicated by a reduction of the specific binding of 3H-nisoxetine to the NET in preparations of cerebral cortex (F(3,16)=4.33, p(3,16)=4.34, p. |
| 參考文獻(xiàn) | |
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| 研究領(lǐng)域 | |
| 研究領(lǐng)域 | MetabolismTypes of diseaseObesity NeuroscienceProcesses NeuroscienceNeurology processMetabolism NeuroscienceNeurotransmissionReceptors / ChannelsGPCRSerotonin Receptors Signal TransductionSignaling PathwayG Protein SignalingGPCR Drug DiscoverySmall Molecule DrugLead Compound Discovery |
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