
簡(jiǎn)要描述:Propantheline bromide 50-34-0Propantheline bromide competitively antagonizes acetylcholine activity mediated by muscarinic receptors at neuroeffector sites on smooth muscle and exocrine gland cells.
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Product Category詳細(xì)介紹
| 品牌 | absin | CAS | 50-34-0 |
|---|---|---|---|
| 分子式 | C23H30BrNO3 | 純度 | 98% |
| 分子量 | 448.4 | 貨號(hào) | abs47027446 |
| 規(guī)格 | 100mg | 供貨周期 | 現(xiàn)貨 |
| 主要用途 | is the bromide salt form of propanthelin | 應(yīng)用領(lǐng)域 | 化工,生物產(chǎn)業(yè),農(nóng)林牧漁,制藥/生物制藥,綜合 |
Propantheline bromide 50-34-0
| 產(chǎn)品描述 | |
| 描述 | Propantheline bromide competitively antagonizes acetylcholine activity mediated by muscarinic receptors at neuroeffector sites on smooth muscle and exocrine gland cells. Propantheline Bromide is the bromide salt form of propantheline, a quaternary ammonium compound structurally related to belladonna alkaloids. An aspartic acid residue present in the N-terminal portion of the third transmembrane helix of the muscarinic receptor is believed to form an ionic bond with the tertiary or quaternary nitrogen of the antagonist. Antagonism leads to a reduction of exocrine glands secretions and to relax the bronchial muscle and reduce tone and motility of intestinal smooth muscle. |
| 純度 | 98% |
| 儲(chǔ)存/保存方法 | Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution. |
| 基本信息 | |
| 別名 | 溴丙胺tai林;普魯本辛;溴化丙胺太林 |
| 外觀 | 白色或類白色結(jié)晶性粉末 |
| 可溶性/溶解性 | DMSO :89 mg/mL (198.48 mM) |
| 生物活性 | |
| 靶點(diǎn) | mAChR |
| 參考文獻(xiàn) | |
| 參考文獻(xiàn) |
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| 研究領(lǐng)域 | |
| 研究領(lǐng)域 | Neuroscience Drug DiscoverySmall Molecule DrugLead Compound Discovery |
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