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    首頁(yè) > 產(chǎn)品中心 > 生化試劑 > 小分子化合物 > abs47027446Propantheline bromide 50-34-0

    Propantheline bromide 50-34-0

    簡(jiǎn)要描述:Propantheline bromide 50-34-0
    Propantheline bromide competitively antagonizes acetylcholine activity mediated by muscarinic receptors at neuroeffector sites on smooth muscle and exocrine gland cells.

    • 產(chǎn)品型號(hào):abs47027446
    • 廠商性質(zhì):生產(chǎn)廠家
    • 更新時(shí)間:2025-12-12
    • 訪  問  量:580

    詳細(xì)介紹

    品牌absinCAS50-34-0
    分子式C23H30BrNO3純度98%
    分子量448.4貨號(hào)abs47027446
    規(guī)格100mg供貨周期現(xiàn)貨
    主要用途is the bromide salt form of propanthelin應(yīng)用領(lǐng)域化工,生物產(chǎn)業(yè),農(nóng)林牧漁,制藥/生物制藥,綜合

    Propantheline bromide  50-34-0

    產(chǎn)品描述
    描述

    Propantheline bromide competitively antagonizes acetylcholine activity mediated by muscarinic receptors at neuroeffector sites on smooth muscle and exocrine gland cells. Propantheline Bromide is the bromide salt form of propantheline, a quaternary ammonium compound structurally related to belladonna alkaloids. An aspartic acid residue present in the N-terminal portion of the third transmembrane helix of the muscarinic receptor is believed to form an ionic bond with the tertiary or quaternary nitrogen of the antagonist. Antagonism leads to a reduction of exocrine glands secretions and to relax the bronchial muscle and reduce tone and motility of intestinal smooth muscle.

    純度
    98%
    儲(chǔ)存/保存方法
    Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution.
    基本信息
    別名
    溴丙胺tai林;普魯本辛;溴化丙胺太林
    外觀
    白色或類白色結(jié)晶性粉末
    可溶性/溶解性
    DMSO :89 mg/mL (198.48 mM)
    生物活性
    靶點(diǎn)
    mAChR
    參考文獻(xiàn)
    參考文獻(xiàn)
    • 1. Saitoh H, et al. J Pharmacobiodyn. 1986 Dec; 9(12):1008-14.

    • 2. Trkulja V, et al. Exp Biol Med (Maywood). 2004 Sep; 229(8): 793-805.

    • 3. Mokry J, et al. Bratisl Lek Listy. 2005; 106(4-5):151-4.

    研究領(lǐng)域
    研究領(lǐng)域
    Neuroscience
    Drug DiscoverySmall Molecule DrugLead Compound Discovery
    Propantheline bromide  50-34-0溫馨提示:本產(chǎn)品僅作科研實(shí)驗(yàn)使用,不支持臨床等研究

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