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    首頁 > 產(chǎn)品中心 > 生化試劑 > 小分子化合物 > abs47027448Cephalexin 15686-71-2

    Cephalexin 15686-71-2

    簡要描述:Cephalexin 15686-71-2
    Prednisone is a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties.

    • 產(chǎn)品型號:abs47027448
    • 廠商性質(zhì):生產(chǎn)廠家
    • 更新時間:2025-12-12
    • 訪  問  量:751

    詳細(xì)介紹

    品牌absinCAS15686-71-2
    分子式C16H17N3O4S純度>98%
    分子量347.39貨號abs47027448
    規(guī)格50mg供貨周期現(xiàn)貨
    主要用途is a synthetic glucocorticoid應(yīng)用領(lǐng)域化工,生物產(chǎn)業(yè),農(nóng)林牧漁,制藥/生物制藥,綜合

    Cephalexin 15686-71-2

    產(chǎn)品描述
    描述

    Prednisone is a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties.

    純度
    >98%
    儲存/保存方法
    Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution.
    基本信息
    別名
    tou孢氨芐;Cefalexin;Cephacillin
    外觀
    白色或微黃色結(jié)晶性粉末
    可溶性/溶解性
    DMSO : 2 mg/mL (5.75 mM)

    Water :10 mg/mL (28.78 mM)
    生物活性
    In vitro(體外研究)
    Cephalexin uptake by human MATE1-expressing human embryonic kidney 293 cells exhibits saturable kinetics with K(m) = 5.9 mM and a bell-shaped pH profile with a maximum at pH 7.0. Cephalexin results in overestimation of glucose concentration, but only in the samples that contain the highest antimicrobial concentration (2,400microg/mL) and only for the tablet. Cephalexin increases the activity of superficial mucous cells and orifice mucous cells of gastric glands, and inhibits the activity of cervix mucous cells.
    In vivo(體內(nèi)研究)
    Cephalexin causes a slight prolongation of 1-stage prothrombin time (PT) and activated partial thromboplastin time (PTT) and slight decrease in fibrinogen concentration in healthy dogs. Cephalexin causes a significant increase in 1-stage PT and activated PTT, amoxicillin causes a significant increase in activated PTT, and enrofloxacin causes a significant decrease in fibrinogen concentration. Cephalexin results in high numbers of E. coli producing plasmid-mediated CMY-2 β-lactamase at the end of the treatment period in dogs.
    參考文獻
    參考文獻
    • 1. Williamson R, et al. Antimicrob Agents Chemother. 1980 Oct;18(4):629-37.

    • 2. Ganapathy ME, et al. J Biol Chem. 2000 Jan 21;275(3):1699-707

    • 3. Mitsuoka K, et al. Drug Metab Dispos. 2007 Mar;35(3):356-62.

    研究領(lǐng)域
    研究領(lǐng)域
    MetabolismTypes of disease
    Drug DiscoverySmall Molecule DrugLead Compound Discovery
    Cephalexin 15686-71-2溫馨提示:本產(chǎn)品僅作科研實驗使用,不支持臨床等研究

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