
簡(jiǎn)要描述:Vecuronium bromide 50700-72-6Vecuronium (bromide) is a muscle relaxant in the category of non-depolarizing blocking agents.
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| 品牌 | absin | CAS | 50700-72-6 |
|---|---|---|---|
| 分子式 | C34H57BrN2O4 | 純度 | >98% |
| 分子量 | 637.73 | 貨號(hào) | abs47027775 |
| 規(guī)格 | 10mg | 供貨周期 | 現(xiàn)貨 |
| 主要用途 | is a muscle relaxant | 應(yīng)用領(lǐng)域 | 化工,生物產(chǎn)業(yè),農(nóng)林牧漁,制藥/生物制藥,綜合 |
Vecuronium bromide 50700-72-6
| 產(chǎn)品描述 | |
| 描述 | Vecuronium (bromide) is a muscle relaxant in the category of non-depolarizing blocking agents. |
| 純度 | >98% |
| 儲(chǔ)存/保存方法 | Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution. |
| 基本信息 | |
| 別名 | 維ku溴銨;ORG NC 45 |
| 外觀 | 白色或類白色粉末 |
| 可溶性/溶解性 | DMSO : 93 mg/mL (145.8 mM) Ethanol : 93 mg/mL (145.8 mM) Water : 4 mg/mL (6.27 mM) |
| 生物活性 | |
| In vitro(體外研究) | Vecuronium inhibits both forms of the muscle-type acetylcholine receptor with IC50 of 1-2 mM. Vecuronium combined with methylprednisolone shows additive effects on both receptor forms, which is best described by a two-site model, with each site independent. Vecuronium interferes with nicotinic processes in the carotid body and inhibits the chemoreceptor neural response to hypoxia. Vecuronium significantly attenuates the increase in CSNA (DeltaCSNA) in response to hypoxia in the carotid body. |
| In vivo(體內(nèi)研究) | Vecuronium (a monoquaternary ammonium compound) has a higher biliary clearance than pancuronium (a bisquaternary ammonium compound) in the rats. |
| 參考文獻(xiàn) | |
| 參考文獻(xiàn) |
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| 研究領(lǐng)域 | |
| 研究領(lǐng)域 | Neuroscience CancerTumor biomarkers Drug DiscoverySmall Molecule DrugLead Compound Discovery |
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