
簡要描述:3,3',5-Triiodo-L-thyronine 6893-02-3Liothyronine is a T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4).
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| 品牌 | absin | CAS | 6893-02-3 |
|---|---|---|---|
| 分子式 | C15H12I3NO4 | 純度 | >98% |
| 分子量 | 650.97 | 貨號 | abs47027804 |
| 規(guī)格 | 10mg | 供貨周期 | 現(xiàn)貨 |
| 主要用途 | used by the tissues is mainly T3. | 應(yīng)用領(lǐng)域 | 化工,生物產(chǎn)業(yè),農(nóng)林牧漁,制藥/生物制藥,綜合 |
3,3',5-Triiodo-L-thyronine 6893-02-3
| 產(chǎn)品描述 | |
| 描述 | Liothyronine is a T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3. |
| 純度 | >98% |
| 儲存/保存方法 | Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution. |
| 基本信息 | |
| 別名 | 三碘甲狀腺原氨酸;碘噻羅寧;甲碘安; T3;L-3,3',5-Triiodothyronine;Liothyronine;Tresitope |
| 外觀 | Off-white to pale yellow powder |
| 可溶性/溶解性 | DMSO : 50 mg/mL (76.81 mM; Need ultrasonic) |
| 生物活性 | |
| 靶點 | TRα,TRβ |
| In vitro(體外研究) | Triiodothyronine (0.01-0.1 μM) results in a decrease in the TRalpha1:TRalpha2 mRNA ratio in HepG2 cells. High liothyronine levels induces a low TRalpha1:TRalpha2 ratio which can protect the cell from excessive triiodothyronine-induced gene expression. |
| 研究領(lǐng)域 | |
| 研究領(lǐng)域 | CancerCancer Metabolism CancerTumor biomarkers NeuroscienceEndocrine system Drug DiscoverySmall Molecule DrugLead Compound Discovery |
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