
簡要描述:Torezolid 856866-72-3Torezolid (TR-701; tedizolid) is a novel oxazolidinone for gram-positive infections.
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Product Category詳細(xì)介紹
| 品牌 | absin | CAS | 856866-72-3 |
|---|---|---|---|
| 分子式 | C17H15FN6O3 | 純度 | >98% |
| 分子量 | 370.34 | 貨號 | abs47027851 |
| 規(guī)格 | 50mg | 供貨周期 | 現(xiàn)貨 |
| 主要用途 | is a novel oxazolidinone | 應(yīng)用領(lǐng)域 | 化工,生物產(chǎn)業(yè),農(nóng)林牧漁,制藥/生物制藥,綜合 |
Torezolid 856866-72-3
| 產(chǎn)品描述 | |
| 描述 | Torezolid (TR-701; tedizolid) is a novel oxazolidinone for gram-positive infections. |
| 純度 | >98% |
| 儲存/保存方法 | Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution. |
| 基本信息 | |
| 別名 | 特地唑胺; TR 700;Torezolid;DA-7157 |
| 外觀 | White to Off-White Solid |
| 可溶性/溶解性 | DMSO : 10 mg/mL (27.00 mM; Need ultrasonic) |
| 生物活性 | |
| In vitro(體外研究) | Tedizolid (0.25 μg/mL) inhibits all 28 clinical isolates of PRSP, and is 4-fold more potent than linezolid against PRSP. |
| In vivo(體內(nèi)研究) | For mice infected with PSSP type III, the 100% survival rate is achieved with tedizolid phosphate at a minimum total daily dose of 10 mg/kg. Lungs of infected mice treated with tedizolid phosphate show less severe inflammation and edema, as indicated by the mean scores for inflammation and edema. |
| 研究領(lǐng)域 | |
| 研究領(lǐng)域 | Drug DiscoverySmall Molecule DrugLead Compound Discovery |
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