全國服務咨詢熱線：
18438616290
<b id="grzca"><menuitem id="grzca"></menuitem></b>
18438616290
簡要描述：Carbidopa Hydrate 38821-49-7Carbidopa ((S)-(-)-Carbidopa) monohydrate, a peripheral decarboxylase inhibitor, can be used for the research of Parkinson's disease.
產(chǎn)品型號：abs47027914廠商性質(zhì)：生產(chǎn)廠家更新時間：2026-01-07訪 問 量：587產(chǎn)品分類
Product Category詳細介紹
| 品牌 | absin | CAS | 38821-49-7 |
|---|---|---|---|
| 分子式 | C10H16N2O5 | 純度 | ≥98% |
| 分子量 | 244.24 | 貨號 | abs47027914 |
| 規(guī)格 | 10mg | 供貨周期 | 現(xiàn)貨 |
| 主要用途 | used for the research of Parkinson's dis | 應用領域 | 化工,生物產(chǎn)業(yè),農(nóng)林牧漁,制藥/生物制藥,綜合 |
Carbidopa Hydrate 38821-49-7
| 產(chǎn)品描述 | |
| 描述 | Carbidopa ((S)-(-)-Carbidopa) monohydrate, a peripheral decarboxylase inhibitor, can be used for the research of Parkinson's disease. Carbidopa monohydrate is a selective aryl hydrocarbon receptor (AhR) modulator. Carbidopa monohydrate inhibits pancreatic cancer cell and tumor growth. |
| 純度 | ≥98% |
| 儲存/保存方法 | Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution. |
| 基本信息 | |
| 別名 | 卡比duo巴水合物；S(-)-Carbidopa；Carbidopa monohydrate；(S)-(-)-Carbidopa monohydrate |
| 外觀 | White powder |
| 可溶性/溶解性 | 10 mM in DMSO |
| 生物活性 | |
| In vitro(體外研究) | Carbidopa ((S)-(-)-Carbidopa) monohydrate exhibits activities similar to that described for other AhR ligands in BχPC3 and Capan-2 cells, namely the induction of CYP1A1 and CYP1A2, which are inhibited by AhR antagonists such as CH223191. Carbidopa, a aromatic-L-amino acid decarboxylase inhibitor, is selectively cytotoxic to human pulmonary carcinoid and small cell lung carcinoma cells. Carbidopa is lethal (IC50=29 μM). |
| In vivo(體內(nèi)研究) | Carbidopa monohydrate also induces nuclear uptake of the AhR, and in vivo studies show that carbidopa at a dose of 1 mg/mouse significantly inhibits tumor growth in athymic nude mice bearing BχPC3 cells as xenografts. |
| 研究領域 | |
| 研究領域 | Signal TransductionMetabolism Drug DiscoverySmall Molecule DrugLead Compound Discovery |
產(chǎn)品咨詢
地址：上海市浦東新區(qū)新浩路58號申江科創(chuàng)園18棟
郵箱：
傳真：