
簡要描述:Tipiracil HCl 183204-72-0Tipiralacil, also known as TPI, is a thymidine phosphorylase inhibitor (TPI). Tipiracil is one of the active components in TAS-102,
產(chǎn)品分類
Product Category詳細(xì)介紹
| 品牌 | absin | CAS | 183204-72-0 |
|---|---|---|---|
| 分子式 | C9H12Cl2N4O2 | 純度 | 98% |
| 分子量 | 279.12 | 貨號 | abs47028013 |
| 規(guī)格 | 5mg | 供貨周期 | 現(xiàn)貨 |
| 主要用途 | is a thymidine phosphorylase inhibitor | 應(yīng)用領(lǐng)域 | 化工,生物產(chǎn)業(yè),農(nóng)林牧漁,制藥/生物制藥,綜合 |
Tipiracil HCl 183204-72-0
| 產(chǎn)品描述 | |
| 描述 | Tipiralacil, also known as TPI, is a thymidine phosphorylase inhibitor (TPI). Tipiracil is one of the active components in TAS-102, which is an anticancer drug candidate currently in clinical trials |
| 純度 | 98% |
| 儲存/保存方法 | Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution. |
| 基本信息 | |
| 可溶性/溶解性 | 10 mM in DMSO |
| 生物活性 | |
| 靶點(diǎn) | Nucleoside Antimetabolite_Analog |
| In vitro(體外研究) | Tipiracil has antiangiogenic effect, and inhibits proliferation of endothelial cells. Tipiracil is a potent inhibitor of thymidine phosphorylase, which is the enzyme that degrades FTD. |
| In vivo(體內(nèi)研究) | |
| 參考文獻(xiàn) | |
| 參考文獻(xiàn) |
|
| 研究領(lǐng)域 | |
| 研究領(lǐng)域 | EpigeneticsDNA / RNADNA SynthesisOther MetabolismPathways and ProcessesMetabolic signaling pathwaysNucleotide metabolismPurine and pyrimidine synthesis Drug DiscoverySmall Molecule DrugLead Compound Discovery |
產(chǎn)品咨詢
