Ulipristal acetate 126784-99-4

簡要描述：Ulipristal acetate 126784-99-4
Ulipristal acetate(CDB2914) is a novel selective progesterone receptor modulator (SPRM) for the treatment of benign gynecological conditions such as uterine myoma.

產(chǎn)品型號：abs47028068
廠商性質(zhì)：生產(chǎn)廠家
更新時間：2026-01-15
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詳細介紹

品牌	absin	CAS	126784-99-4
分子式	C30H37NO4	純度	99%
分子量	475.62	貨號	abs47028068
規(guī)格	5mg	供貨周期	現(xiàn)貨
主要用途	is a novel selective progesterone recept	應(yīng)用領(lǐng)域	化工,生物產(chǎn)業(yè),農(nóng)林牧漁,制藥/生物制藥,綜合

Ulipristal acetate 126784-99-4

產(chǎn)品描述
描述	Ulipristal acetate(CDB2914) is a novel selective progesterone receptor modulator (SPRM) for the treatment of benign gynecological conditions such as uterine myoma.
純度	99%
儲存/保存方法	Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
基本信息
可溶性/溶解性	10 mM in DMSO
生物活性
靶點	Progesterone receptor
In vitro(體外研究)	Ulipristal acetate has partial agonistic as well as antagonistic effects on the progesterone receptor. It also binds to theglucocorticoid receptor, but has no relevant affinity to the estrogen, androgen and mineralocorticoid receptors.
In vivo(體內(nèi)研究)	Based on clinical trials, ulipristal acetate seems to be a reasonably tolerable and effective method of emergency contraception when used within 120 hours of intercourse. Ulipristal acetate is at least as effective as LNG when used within the first 72 hours after unprotected intercourse. However, ulipristal acetate may be more effective than LNG when used between 72 to 120 hours after unprotected intercourse, extending the window of opportunity for emergency contraception.
參考文獻
參考文獻	1. Pohl O, et al. Int J Clin Pharmacol Ther. 2013 Jan;51(1):26-33. 2. Williams AR, et al. Int J Gynecol Pathol. 2012 Nov;31(6):556-69.

研究領(lǐng)域

CancerSignal transductionNuclear signalingNuclear hormone receptorsProgesterone

CancerTumor biomarkersReceptors

EpigeneticsNuclear Signaling PathwaysNuclear ReceptorsProgesterone

EpigeneticsTranscriptionDomain FamiliesZinc Finger

NeuroscienceDevelopment

NeuroscienceProcesses

NeuroscienceEndocrine systemGonadotrophic axis

Signal TransductionSignaling PathwayNuclear SignalingNuclear Hormone ReceptorsProgesterone

Drug DiscoverySmall Molecule DrugLead Compound Discovery

Ulipristal acetate 126784-99-4溫馨提示：本產(chǎn)品僅作科研實驗使用，不支持臨床等研究

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Ulipristal acetate 126784-99-4

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