Siglec-3/CD33 （C-6His）

簡要描述：愛必信特色產(chǎn)品線（全部現(xiàn)貨）：
二抗、標簽抗體、對照抗體；WB相關(guān)：ECL發(fā)光液、預染marker、預制膠；IHC相關(guān)：二抗試劑盒、組化筆；IP/CoIP試劑盒；細胞因子、信號通路調(diào)節(jié)劑；血清、BSA、蛋白酶K、CTB、TTX、CEE；凋亡試劑盒、呼吸爆發(fā)試劑盒；動植物提取物...

產(chǎn)品型號：abs04039
廠商性質(zhì)：生產(chǎn)廠家
更新時間：2025-09-25
訪問量：2737

產(chǎn)品咨詢聯(lián)系我們

產(chǎn)品分類

Product Category

細胞生物學

重組蛋白原代細胞分離細胞培養(yǎng) 細胞檢測細胞/組織處理外泌體研究其它動物血清 3D/類器官培養(yǎng)

查看全部

相關(guān)文章

詳細介紹

品牌	absin	規(guī)格	10ug
供貨周期	一周

概述
描述	Recombinant Mouse Sialic Acid Binding Ig-like Lectin 3 is produced by our Mammalian expression system and the target gene encoding Asp18-Glu240 is expressed with a 6His tag at the C-terminus.
別名	CD33/Myeloid cell surface antigen CD33/Sialic acid-binding Ig-like lectin 3/Siglec-3/Siglec3
形態(tài)	Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.
來源	Human Cells
氨基酸序列	DLEFQLVAPESVTVEEGLCVHVPCSVFYPSIKLTLGPVTGSWLRKGVSLHEDSPVATSDPRQLVQ KATQGRFQLLGDPQKHDCSLFIRDAQKNDTGMYFFRVVREPFVRYSYKKSQLSLHVTSLSRTPDI IIPGTLEAGYPSNLTCSVPWACEQGTPPTFSWMSTALTSLSSRTTDSSVLTFTPQPQDHGTKLTC LVTFSGAGVTVERTIQLNVTRKSGQMREVDHHHHHH
內(nèi)毒素水平	Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test.
Accession #	Q63994

性能
背景	Mouse myeloid cell surface antigen CD33(CD33) is a member of the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. CD33 contains one Ig-like C2-type domain and one Ig-like V-type domain. CD33 is a putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. CD33 preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, CD33 may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. CD33 induces apoptosis in acute myeloid leukemia. CD33 is becoming increasingly important as a target of antibody-mediated therapy in acute myeloid leukaemia (AML).
溶解方法	Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
保存方法	Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
純度	Greater than 95% as determined by reducing SDS-PAGE.

產(chǎn)品咨詢

留言框

產(chǎn)品：
您的單位：
您的姓名：
聯(lián)系電話：
常用郵箱：
省份：
詳細地址：
補充說明：
驗證碼：

請輸入計算結(jié)果（填寫阿拉伯數(shù)字），如：三加四=7

上一篇：abs04040PD-1/CD279 （C-Fc）
下一篇：abs04036ErbB2/HER2 （C-6His）

Siglec-3/CD33 （C-6His）

留言框

產(chǎn)品：

您的單位：

您的姓名：

聯(lián)系電話：

常用郵箱：

省份：

詳細地址：

補充說明：

驗證碼：