Histamine 51-45-6

簡要描述：Histamine 51-45-6
Histamine is an organic nitrogenous compound involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter.

產(chǎn)品型號：abs47027417
廠商性質(zhì)：生產(chǎn)廠家
更新時間：2025-12-11
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品牌	absin	CAS	51-45-6
分子式	C5H9N3	純度	≥98%
分子量	111.15	貨號	abs47027417
規(guī)格	10mg	供貨周期	現(xiàn)貨
主要用途	is an organic nitrogenous	應(yīng)用領(lǐng)域	化工,生物產(chǎn)業(yè),農(nóng)林牧漁,制藥/生物制藥,綜合

Histamine 51-45-6

產(chǎn)品描述
描述	Histamine is an organic nitrogenous compound involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter.
純度	≥98%
儲存/保存方法	Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
基本信息
別名	組胺；Ergamine
外觀	白色或淡黃色結(jié)晶粉末
可溶性/溶解性	Ethanol : Soluble Water : ≥34 mg/mL
生物活性
靶點	Histamine Receptor
In vitro(體外研究)	Histamine stimulates the proliferation of human articular chondrocytes in culture. Histamine is reported to modify the behaviour of many cell types in vitro, including chondrocytes, fibroblasts, macrophages, epithelial cells, endothelial cells, and T cells. Histamine also modulates the production of many cytokines and the expression of their receptors. Histamine regulates cellular processes through the expression of histamine receptors. Histamine stimulates the production of matrix metalloproteinases (MMPs)-13 and -3 (collagenase 3 and stromelysin-1, respectively) by histidine decarboxylase (HAC) in vitro.
In vivo(體內(nèi)研究)	Histamine has a recognised role in allergic and inflammatory reactions and is an important modulator of numerous physiological processes, including cell proliferation, angiogenesis, and vasopermeability. Histamine dilates vasculature, increases blood flow, while it induces hyperpermeability in venula. It disrupts endothelial barrier formation of venula indicated by changes in vascular endothelial cadherin (VE-cadherin) localization at endothelial cell junction.
參考文獻
參考文獻	1. Hardie RC. Nature. 1989 Jun 29;339(6227):704-6. 2. Pantazis A, et al. J Neurosci. 2008 Jul 16; 28(29):7250-9. 3. Lee HS, et al. Brain Res. 2005 May 10;1043(1-2):65-75.

研究領(lǐng)域
研究領(lǐng)域	Immunology Drug DiscoverySmall Molecule DrugLead Compound Discovery

Histamine 51-45-6溫馨提示：本產(chǎn)品僅作科研實驗使用，不支持臨床等研究

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Histamine 51-45-6

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