Drospirenone 67392-87-4

簡要描述：Drospirenone 67392-87-4
Drospirenone is a synthetic progestin that is an analog to spironolactone.

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品牌	absin	CAS	67392-87-4
分子式	C24H30O3	純度	99%
分子量	366.49	貨號(hào)	abs47027748
規(guī)格	10mg	供貨周期	現(xiàn)貨
主要用途	is a synthetic progestin	應(yīng)用領(lǐng)域	化工,生物產(chǎn)業(yè),農(nóng)林牧漁,制藥/生物制藥,綜合

Drospirenone 67392-87-4

產(chǎn)品描述
描述	Drospirenone is a synthetic progestin that is an analog to spironolactone. It is found in a number of birth control formulations. Drospirenone differs from other synthetic progestins in that its pharmacological profile in preclinical studies shows it to be closer to the natural progesterone. As such it has anti-mineralocorticoid properties, counteracts the estrogen-stimulated activity of the renin-angiotensin-aldosterone system, and is not androgenic. It was shown in animal studies that drospirenone exhibits antiandrogenic activity judging from accessory sex gland growth in castrated, androgen-treated, juvenile rats.
純度	99%
儲(chǔ)存/保存方法	Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
基本信息
別名	屈螺酮；Dihydrospirorenone
外觀	白色至類白色結(jié)晶粉末
可溶性/溶解性	DMSO : 68 mg/mL (185.5 mM) Ethanol : 9 mg/mL (24.6 mM)
生物活性
靶點(diǎn)	Progesterone Receptor
參考文獻(xiàn)
參考文獻(xiàn)	1. Bray JD, et al. J Steroid Biochem Mol Biol. 2005 Dec;97(4):328-41. 2. Maia H Jr, et al. Eur J Contracept Reprod Health Care. 2010 Feb;15(1):35-40. 3. Fuhrmann U, et al. Contraception. 1996 Oct;54(4):243-51. 4. Koitka M, et al. J Pharm Biomed Anal. 2010 Feb 5;51(3):664-78. 5. Arias-Loza PA, et al. Hypertension. 2006 Nov;48(5):994-1001.

研究領(lǐng)域

CancerSignal transductionNuclear signalingNuclear hormone receptorsProgesterone

CancerTumor biomarkersReceptors

EpigeneticsNuclear Signaling PathwaysNuclear ReceptorsProgesterone

EpigeneticsTranscriptionDomain FamiliesZinc Finger

NeuroscienceDevelopment

NeuroscienceProcesses

NeuroscienceEndocrine systemGonadotrophic axis

Signal TransductionSignaling PathwayNuclear SignalingNuclear Hormone ReceptorsProgesterone

Drug DiscoverySmall Molecule DrugLead Compound Discovery

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