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18438616290
簡要描述：PI3065 955977-50-1PI-3065 is a novel potent and selective PI3K p110δ inhibitor with IC50 of 15 nM; exhibits > 100 fold selectivity against p110α, p110β, p110γ, DNA-PK and mTOR.
產(chǎn)品型號：abs47027897廠商性質(zhì)：生產(chǎn)廠家更新時間：2026-01-06訪 問 量：761產(chǎn)品分類
Product Category詳細(xì)介紹
| 品牌 | absin | CAS | 955977-50-1 |
|---|---|---|---|
| 分子式 | C27H31FN6OS | 純度 | 98% |
| 分子量 | 506.64 | 貨號 | abs47027897 |
| 規(guī)格 | 2mg | 供貨周期 | 現(xiàn)貨 |
| 主要用途 | is a novel potent and selective PI3K p11 | 應(yīng)用領(lǐng)域 | 化工,生物產(chǎn)業(yè),農(nóng)林牧漁,制藥/生物制藥,綜合 |
PI3065 955977-50-1
| 產(chǎn)品描述 | |
| 描述 | PI-3065 is a novel potent and selective PI3K p110δ inhibitor with IC50 of 15 nM; exhibits > 100 fold selectivity against p110α, p110β, p110γ, DNA-PK and mTOR. |
| 純度 | 98% |
| 儲存/保存方法 | Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution. |
| 基本信息 | |
| 別名 | PI3065 |
| 外觀 | White to off white powder |
| 可溶性/溶解性 | DMSO : 25 mg/mL (49.34 mM; Need ultrasonic) |
| 生物活性 | |
| 靶點 | p110α；p110β；p110δ |
| In vitro(體外研究) | PI-3065 exhibits no inhibition of the growth of 4T1 cells, which do not express detectable levels of p110δ. |
| In vivo(體內(nèi)研究) | PI-3065 (75 mg/kg, p.o.) inhibits the growth of 4T1 tumours in the BALB/c mice without obvious body weight loss. |
| 研究領(lǐng)域 | |
| 研究領(lǐng)域 | CancerCancer Metabolism Drug DiscoverySmall Molecule DrugLead Compound Discovery |
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